Search results for " Esophageal and Gastric Varices"

showing 8 items of 8 documents

Mortality risk according to different clinical characteristics of first episode of liver decompensation in cirrhotic patients: a nationwide, prospect…

2013

Abstract OBJECTIVES: The occurrence of decompensation marks a crucial turning point in the course of cirrhosis. The purpose of this study was to assess the risk of mortality according to the clinical characteristics of first decompensation, considering also the impact of acute-on-chronic liver failure (AoCLF). METHODS: We conducted a prospective nationwide inception cohort study in Italy. Decompensation was defined by the presence of ascites, either overt or detected by ultrasonography (UD), gastroesophageal variceal bleeding (GEVB), and hepatic encephalopathy (HE). AoCLF was defined according to the Asian Pacific Association for the Study of the Liver criteria. Multivariable Cox proportion…

AdultLiver CirrhosisMalemedicine.medical_specialtyPediatricsCarcinoma HepatocellularCirrhosisAdolescentmedicine.medical_treatmentCirrhosis Mortality Liver decompensation CohortLiver transplantationEsophageal and Gastric VaricesSeverity of Illness IndexYoung AdultSeverity of illnessmedicineHumansProspective StudiesYoung adultIntensive care medicineProspective cohort studyHepatic encephalopathyAgedProportional Hazards ModelsAged 80 and overFirst episodeHepatologybusiness.industryLiver NeoplasmsGastroenterologyAscitesMiddle Agedmedicine.diseaseLiver TransplantationAdolescent; Adult; Aged; Aged 80 and over; Ascites; Carcinoma Hepatocellular; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Hepatic Encephalopathy; Humans; Italy; Liver Cirrhosis; Liver Failure; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Prospective Studies; Severity of Illness Index; Young AdultItalyCirrhosisHepatic EncephalopathyMultivariate AnalysisCohortFemaleGastrointestinal HemorrhagebusinessLiver FailureFollow-Up Studies
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Including Ratio of Platelets to Liver Stiffness Improves Accuracy of Screening for Esophageal Varices That Require Treatment

2021

International audience; Background & aims: Based on platelets and liver stiffness measurements, the Baveno VI criteria (B6C), the expanded B6C (EB6C), and the ANTICIPATE score can be used to rule out varices needing treatment (VNT) in patients with compensated chronic liver disease. We aimed to improve these tests by including data on the ratio of platelets to liver stiffness.Methods: In a retrospective analysis of data from 10 study populations, collected from 2004 through 2018, we randomly assigned data from 2368 patients with chronic liver disease of different etiologies to a derivation population (n = 1579; 15.1% with VNT, 50.2% with viral hepatitis, 28.9% with nonalcoholic fatty liver …

Blood PlateletsLiver CirrhosisNoninvasive Diagnosismedicine.medical_specialtyCirrhosis[SDV]Life Sciences [q-bio]PopulationEsophageal and Gastric VaricesChronic liver diseaseSeverity of Illness IndexGastroenterologyEnd Stage Liver Disease03 medical and health sciencesLiver disease0302 clinical medicineModel for End-Stage Liver DiseaseEsophageal varicesInternal medicineNonalcoholic fatty liver diseasemedicineHumanseducationBaveno VI CriteriaRetrospective Studieseducation.field_of_studyHepatologybusiness.industryGastroenterologyRetrospective cohort studyPortal Hypertensionmedicine.disease3. Good healthMELDCirrhosis030220 oncology & carcinogenesisElasticity Imaging Techniques030211 gastroenterology & hepatologybusinessBaveno VI Criteria Blood Platelets Cirrhosis Elasticity Imaging Techniques End Stage Liver Disease Esophageal and Gastric Varices Humans Liver Cirrhosis MELD Noninvasive Diagnosis Portal Hypertension Retrospective Studies Severity of Illness Index
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Hemostatic balance in patients with liver cirrhosis: Report of a consensus conference.

2016

Abstract Patients with cirrhosis present with hemostatic alterations secondary to reduced availability of pro-coagulant and anti-coagulant factors. The net effect of these changes is a rebalanced hemostatic system. The Italian Association of the Study of the Liver (AISF) and the Italian Society of Internal Medicine (SIMI) promoted a consensus conference on the hemostatic balance in patients with cirrhosis. The consensus process started with the review of the literature by a scientific board of experts and ended with a formal consensus meeting in Rome in December 2014. The statements were graded according to quality of evidence and strength of recommendations, and approved by an independent …

Liver CirrhosisCirrhosisBleeding; Cirrhosis; Hemostasis; Thrombosis; Hepatology; GastroenterologySettore MED/09 - Medicina InternaBleeding; Cirrhosis; Hemostasis; Thrombosis; Anticoagulants; Coagulants; Drug Monitoring; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Postoperative Hemorrhage; Thrombosis; Blood Coagulation Tests; Hemostasis; Hepatology; Gastroenterology0302 clinical medicineEsophageal and Gastric VariceBlood coagulation testConsensus conferenceGastroenterologyThrombosisOptimal managementCirrhosisCoagulant030220 oncology & carcinogenesisThrombosi030211 gastroenterology & hepatologyBlood Coagulation TestsDrug MonitoringGastrointestinal HemorrhageHumanmedicine.medical_specialtyLiver CirrhosiBleeding; Cirrhosis; Hemostasis; Thrombosis; Gastroenterology; HepatologyPostoperative HemorrhageEsophageal and Gastric VaricesNO03 medical and health sciencesInternal medicinemedicineHumansIn patientIntensive care medicineHemostasisCirrhosiHepatologybusiness.industryCoagulantsBleeding; Cirrhosis; Hemostasis; ThrombosisBleedingAnticoagulantAnticoagulantsThrombosisHepatologyHemostasiBlood Coagulation Testmedicine.diseaseSurgeryHemostasisbusinessDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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Assessing the impact of COVID-19 on the management of patients with liver diseases: A national survey by the Italian association for the study of the…

2020

Abstract Background The COVID-19 pandemic had a huge impact on national and regional health systems. The impact of SARS-CoV-2 on the quality of care for patients with liver disease is still unknown. Aims The Italian Association for the Study of the Liver (AISF) conducted a survey to assess the impact of SARS-CoV-2 on hepatology units activities in Italy. Methods A prospective web-based survey was proposed to all AISF active members. The survey was available online from April 8 2020, to May 3 2020, (lockdown phase in Italy). Results 194 AISF members answered the questionnaire, most of whom were specialists in Gastroenterology (41%) or Internal Medicine (28%), and worked in Northern Italy (51…

Liver CirrhosisLiver disease0302 clinical medicineSurveys and QuestionnairesPandemicAmbulatory CareMass ScreeningParacentesisViralChronicLiver DiseasesLiver NeoplasmsGastroenterologyHepatology Covid-19 SARS COV-2Hepatitis BHepatitis CHospitalizationCovid-19; Hepatology; SARS COV-2Italy030220 oncology & carcinogenesis030211 gastroenterology & hepatologyCoronavirus Infectionsmedicine.medical_specialtyCarcinoma HepatocellularCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViralEsophageal and Gastric VaricesAntiviral AgentsArticle03 medical and health sciencesBetacoronavirusHepatitis B ChronicInternal medicinemedicineHumansPandemicsMass screeningQuality of Health CareHepatologybusiness.industrySARS-CoV-2SARS COV-2CarcinomaOutbreakCOVID-19HepatocellularPneumoniaHepatitis C ChronicHepatologymedicine.diseaseNorthern italyLiver TransplantationEmergency medicineChronic DiseaseCovid-19; Hepatology; SARS COV-2; Ambulatory Care; Antiviral Agents; Betacoronavirus; COVID-19; Carcinoma Hepatocellular; Chronic Disease; Coronavirus Infections; Esophageal and Gastric Varices; Gastroenterology; Hepatitis B Chronic; Hepatitis C Chronic; Hospitalization; Humans; Italy; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Liver Transplantation; Mass Screening; Pandemics; Paracentesis; Pneumonia Viral; Quality of Health Care; SARS-CoV-2; Surveys and Questionnairesbusiness
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A New Sampling Method for Spleen Stiffness Measurement Based on Quantitative Acoustic Radiation Force Impulse Elastography for Noninvasive Assessment…

2014

In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue Quantification (VTTQ)).We measured SS in 54 patients with HCV-related cirrhosis of whom 28 with esophageal varices (EV), 27 with Chronic Hepatitis C (CHC) F1–F3, and 63 healthy controls. VTTQ-SS was significantly higher among cirrhotic patients with EV (3.37 m/s) in comparison with controls (2.19 m/s,P<0.001), CHC patients (2.37 m/s,P<0.001), and cirrhotic patients without EV (2.7 m/s,P<0.001). Moreover, VTTQ-SS was significantly higher among cirrhotic patients without EV in comparison with bot…

Liver CirrhosisMaleGenetics and Molecular Biology (all)CirrhosisData InterpretationImmunology and Microbiology (all)lcsh:MedicineVarices assessementLikelihood ratios in diagnostic testingGastroenterologyBiochemistryEsophageal varicesComputer-AssistedUltrasonographymedicine.diagnostic_testAUROCMedicine (all)General MedicineHepatitis CStatisticalMiddle AgedHepatitis CCirrhosisData Interpretation StatisticalFemaleElastographyViral hepatitisAlgorithmsAged; Algorithms; Data Interpretation Statistical; Elastic Modulus; Esophageal and Gastric Varices; Female; Hepatitis C; Humans; Image Interpretation Computer-Assisted; Liver Cirrhosis; Male; Middle Aged; Reproducibility of Results; Sample Size; Sensitivity and Specificity; Spleen; Stress Mechanical; Biochemistry Genetics and Molecular Biology (all); Immunology and Microbiology (all); Medicine (all)medicine.medical_specialtyArticle SubjectEsophageal and Gastric VaricesStressSensitivity and SpecificityGeneral Biochemistry Genetics and Molecular BiologyInternal medicineElastic ModulusImage Interpretation Computer-AssistedmedicineHumansAcoustic radiation forceImage InterpretationAgedGeneral Immunology and Microbiologybusiness.industrylcsh:RReproducibility of Resultsmedicine.diseaseMechanicalEndoscopySample SizeClinical StudyStress MechanicalbusinessSpleen
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Non-invasive prediction of esophageal varices by stiffness and platelet in non-alcoholic fatty liver disease cirrhosis.

2018

Background & Aims: Baveno VI and expanded Baveno VI criteria can avoid the need for esophagogastroduodenoscopy (EGD) to screen for varices needing treatment (VNT) in a substantial proportion of compensated patients with viral and/or alcoholic cirrhosis. This multicenter, cross-sectional study aims to validate these criteria in patients with compensated cirrhosis due to non-alcoholic fatty liver disease (NAFLD), accounting for possible differences in liver stiffness measurement (LSM) values between M and XL probes. Methods: We assessed 790 patients with NAFLD-related compensated cirrhosis who had EGD within six months of a reliable LSM, measured by FibroScan® using M and/or XL probe. Baveno …

Liver CirrhosisMalemedicine.medical_specialtyAlcoholic liver diseaseCirrhosisVariceEsophageal and Gastric VaricesGastroenterology03 medical and health sciences0302 clinical medicineEsophageal varicesBaveno; Cirrhosis; NAFLD; Stiffness; Varices; Aged; Cross-Sectional Studies; Elasticity Imaging Techniques; Endoscopy Digestive System; Esophageal and Gastric Varices; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Platelet CountNon-alcoholic Fatty Liver DiseaseInternal medicineNAFLDmedicineHumansEndoscopy Digestive SystemBavenoScreening proceduresAgedCirrhosimedicine.diagnostic_testHepatologyEsophagogastroduodenoscopybusiness.industryPlatelet CountFatty liverHepatologyMiddle Agedmedicine.disease3. Good healthCross-Sectional Studies030220 oncology & carcinogenesisStiffneElasticity Imaging Techniques030211 gastroenterology & hepatologyFemaleVaricesbusinessJournal of hepatology
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Monitoring Occurrence of Liver-Related Events and Survival by Transient Elastography in Patients With Nonalcoholic Fatty Liver Disease and Compensate…

2021

[Background & Aims] Patients with advanced fibrosis related to nonalcoholic fatty liver disease (NAFLD) are at risk of developing hepatic and extrahepatic complications. We investigated whether, in a large cohort of patients with NAFLD and compensated advanced chronic liver disease, baseline liver stiffness measurements (LSMs) and their changes can be used to identify patients at risk for liver-related and extrahepatic events.

Liver Cirrhosismedicine.medical_specialtyCarcinoma HepatocellularSettore MED/09 - Medicina InternaNASH; cACLD; prognostic factor; steatohepatitis[SDV]Life Sciences [q-bio]cACLD; NASH; Prognostic Factor; Steatohepatitis; Gastrointestinal Hemorrhage; Humans; Liver; Liver Cirrhosis; Retrospective Studies; Carcinoma Hepatocellular; Elasticity Imaging Techniques; Esophageal and Gastric Varices; Liver Neoplasms; Non-alcoholic Fatty Liver Disease610 Medicine & healthEsophageal and Gastric VaricesChronic liver diseaseGastroenterology03 medical and health sciences0302 clinical medicineNon-alcoholic Fatty Liver DiseaseInterquartile rangeInternal medicineAscitesNonalcoholic fatty liver diseasemedicineHumansComputingMilieux_MISCELLANEOUSRetrospective StudiesSteatohepatitisHepatologybusiness.industryPrognostic FactorsteatohepatitiCarcinomaLiver NeoplasmsHazard ratioGastroenterologyNASHHepatocellularcACLDmedicine.disease3. Good healthLiver030220 oncology & carcinogenesisHepatocellular carcinomaElasticity Imaging Techniques030211 gastroenterology & hepatologySteatohepatitismedicine.symptomGastrointestinal HemorrhageTransient elastographybusiness
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Baveno VII – Renewing consensus in portal hypertension

2022

To expand on the work of previous meetings, a virtual Baveno VII workshop was organised for October 2021. Among patients with compensated cirrhosis or compensated advanced chronic liver disease (cACLD – defined at the Baveno VI conference), the presence or absence of clinically significant portal hypertension (CSPH) is associated with differing outcomes, including risk of death, and different diagnostic and therapeutic needs. Accordingly, the Baveno VII workshop was entitled “Personalized Care for Portal Hypertension”. The main fields of discussion were the relevance and indications for measuring the hepatic venous pressure gradient as a gold standard, the use of non-invasive tools for the …

recommendationLiver CirrhosisCirrhosiHepatologydecompensationtreatmentdiagnosisEsophageal and Gastric VaricesPortal PressurediagnosiCirrhosisHypertension PortalrecommendationsHypertensionHumansElasticity Imaging TechniquesCirrhosis; decompensation; diagnosis; recommendations; treatmentPortalCirrhosis; decompensation; diagnosis; recommendations; treatment; Humans; Liver Cirrhosis; Portal Pressure; Elasticity Imaging Techniques; Esophageal and Gastric Varices; Hypertension Portal
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